Gain comprehensive insights into brain tumors from Dr. Timothy Cloughesy, Professor in the UCLA Department of Neurology, in this 40-minute conference talk from the 20th Annual UCLA Brain Tumor Conference. Explore the Specialized Program of Research Excellence (SPORE) by the National Cancer Institute and delve into the background of brain tumors, including the incidence of primary brain tumors and the causes and risk factors for malignant glioma. Learn about the formation of brain tumors and the complex interaction between tumors and their microenvironment in glioma maintenance. Examine the prognosis and molecular integration into the World Health Organization (WHO) classification, focusing on the integration of molecular data into WHO 2016 criteria for diffuse gliomas. Understand the role of molecular status as a predictive and prognostic marker. Investigate the challenges of measuring the effectiveness of immunotherapy without relying on tumor shrinkage, and discover how neoadjuvant PD-1 therapy improves progression-free survival (PFS) and overall survival (OS) in brain tumor patients. Read more