Learn how to connect a React-based CoreUI frontend with a Python and Flask backend in this comprehensive tutorial. Discover the essential steps to set up a full-stack development environment, including validating Python and Flask applications, adding a development proxy server to the CoreUI frontend, implementing classes for handling GET and POST RESTful requests, connecting routes-based pages to call Python backend APIs, parsing API responses, and rendering data on web pages. Follow along as the instructor guides you through code reviews, setup processes, and practical implementations, ensuring you can verify both GET and POST connections between CoreUI and the Python web server. By the end of this 21-minute video, you'll have the knowledge to build a functional full-stack application using these popular technologies.