Explore the cutting-edge developments in personalized genomic medicine through this comprehensive lecture from the Computational Genomics Summer Institute. Delve into the utilization of large-scale biobanks linked with medical records to advance precision health research. Examine the UCLA ATLAS Community Health Initiative, which leverages genomic diversity for discovery in an EHR-linked biobank. Investigate the impact of pre-existing conditions in Hispanic/Latinx populations on COVID-19 risk factors. Analyze the challenges and implications of individual polygenic risk score estimation in PRS-based risk stratification. Gain insights into powerful genome-wide association studies (GWAS) in admixed populations. Learn about the latest methodologies and findings in genomic medicine, including leveraging diverse biobanks, addressing uncertainties in risk prediction, and advancing precision health research in diverse populations.