Explore the impact of repetitive DNA sequences on complex human traits in this 37-minute lecture from the Computational Genomics Summer Institute. Delve into genome-wide association studies, focusing on short tandem repeats and their contributions to blood and serum traits. Examine cutting-edge research on population-specific repeat expansions and their integration with other genomic data. Learn about challenges in identifying and analyzing tandem repeats from sequencing data, and discover tools and opportunities for further investigation in this rapidly evolving field of computational genomics.