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Intro
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SEQUENCING AND BATCHING ARE KEY CONTRIBUTORS TO LONG TURNAROUND FOR RESEARCH AND CLINICAL SEQUENCING
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GREAT VARIATION IN REQUIRED TURNAROUND FOR CLINICAL AND RESEARCH APPLICATIONS
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OPTICAL ENSEMBLE SEQUENCING BY SYNTHESIS VIA FLUORESCENTLY LABELED REVERSIBLE TERMINATED NUCLEOTIDES
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RAPID NUCLEOTIDE INCORPORATION, IMAGING AND CLEAVAGE
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HIGH PERFORMANCE COMPUTING REQUIRED FOR RAPID IMAGE PROCESSING, BASECALLING AND INTERPRETATION
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A COMBINATION OF GPU AND CPU PROCESSING DELIVERS SPEED & VERSATILITY
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HIGH TECHNICAL REPRODUCIBILITY
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HIGH CORRELATION WITH ILLUMINA NEXTSEQ™ 2000
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SEQUENCING QUALITY METRICS
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ALIGNMENT AND COVERAGE METRICS
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READ ACCURACY AND ERROR MODES
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ACCURACY ACROSS CHALLENGING GENOMIC FEATURES
Description:
Explore a webinar on next-generation sequencing innovations presented by Dr. Timothy Looney, Senior Director of Immunology and Bioinformatics at Singular Genomics. Discover how advancements in chemistry and engineering are revolutionizing DNA sequencing platforms to provide high accuracy, speed, and flexible throughput. Learn about the impact of rapid sequencing and flexible throughput on reducing turnaround time in research and clinical NGS applications. Gain insights into optical ensemble sequencing by synthesis, rapid nucleotide incorporation techniques, and high-performance computing requirements for image processing and basecalling. Examine the technical reproducibility, correlation with Illumina NextSeq™ 2000, sequencing quality metrics, and accuracy across challenging genomic features. Understand the importance of sequencing and batching in research and clinical sequencing turnaround times, and explore the variations in required turnaround for different applications.

Delivering Fast, Flexible Next-Generation Sequencing through Innovations in Chemistry and Engineering

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