Explore the latest insights on gastrointestinal involvement in scleroderma, focusing on the microbiome and cutting-edge research, in this comprehensive 58-minute conference talk from the 2022 National Scleroderma Conference. Join Dr. Elizabeth R. Volkmann, MD, MS, as she delves into the complex relationship between the gut microbiome and scleroderma, discussing how alterations in the microbiome may contribute to disease progression and symptoms. Learn about promising research directions and potential therapeutic approaches that target the microbiome to improve outcomes for scleroderma patients with gastrointestinal complications. Gain valuable knowledge on this important aspect of scleroderma management and stay informed about the latest advancements in the field.