Explore the design, construction, and usage of the draft pangenome in this informative conference talk from the Computational Genomics Summer Institute (CGSI) 2023. Delve into the latest advancements in pangenome research, including the creation of a draft human pangenome reference and its implications for genomic studies. Examine the impact of variable number tandem repeats on gene expression and learn about genotyping common, large structural variations using pangenomes. Discover efficient and accurate genotyping methods across a wide spectrum of variant classes using pangenome-based genome inference. Gain valuable insights into cutting-edge computational genomics techniques and their applications in understanding human genetic diversity.