Explore the critical importance of studying health issues in the space environment through this comprehensive lecture. Delve into the 70-day Bed Rest study, which served as a platform for multiple integrated research studies and standardized measures targeting various physiological systems. Learn about the microgravity space environment, human adaptations, and the methodology behind bedrest studies. Discover how this research platform effectively supports multiple investigations using a small number of subjects to answer numerous research questions. Gain insights from Dr. Patrice Yarbough, a senior scientist at NASA Johnson Space Center, as she shares her expertise on confined isolation human subject studies and the Human Exploration Research Analog habitat. Understand the significance of international bedrest studies and standard measures in advancing our knowledge of space-related health issues.