Explore the groundbreaking achievements in astronomy through this World Science Festival talk featuring Nobel Laureate John Mather. Delve into Mather's leadership of two monumental scientific endeavors: NASA's COBE mission, which solidified the Big Bang theory, and the James Webb Space Telescope, offering unprecedented views of the early universe. Moderated by Brian Greene, this hour-long discussion illuminates how current scientific advancements build upon past discoveries, embodying Isaac Newton's famous quote about standing on the shoulders of giants. Gain insights into the evolution of our understanding of the cosmos and the cutting-edge technologies pushing the boundaries of astronomical observation.