Explore the critical field of virus hunting and pandemic prevention in this 47-minute talk by virologist Nathan Wolfe. Delve into the origins of viruses, human-animal interactions, and the challenges of early detection. Learn about the importance of trust, sustainability, and always-on surveillance in combating viral threats. Examine the risks associated with research and the concept of "unknown unknowns" in epidemiology. Gain insights into Wolfe's perspective as a "catastrophist" and his unique personal life. Conclude with a Q&A session addressing audience inquiries on this vital topic.