Главная
Study mode:
on
1
Intro
2
we can select a series of enzymes from a catalog that will produce some desired industrial compound
3
petroleum/crude oil
4
methyl methacrylate (MMA)
5
advantages of PMMA
6
production of PMMA from crude oil is not sustainable
7
oil in the ground will eventually run out
8
Project Lead: Aaron Korkegian
9
a-methylene-y-butyrolactone (MBL)
10
fermentation host (yeast, bacteria, etc.)
11
enzyme database + efficient algorithm
12
natural substrate
13
the methyl may clash in the active site
14
Proposed Pathway
15
Generating the Enzymes
16
Testing the Enzymes
17
Optimizing the Enzymes
18
Testing the Optimized Enzymes
19
Confirmed Pathway
20
we can modify the ribosomal binding site sequences for any of the enzymes
21
any such reaction can be run in precisely the same large vat with the same material
22
PROFESSOR DAVE EXPLAINS
Description:
Explore the fascinating world of synthetic biology and materials science in this informative video tutorial. Delve into the process of engineering microorganisms to produce Tulipalin A, a compound used in manufacturing plastics without relying on crude oil. Learn about the groundbreaking work being done at biotech firm Arzeda, including the challenges and intricacies of this innovative approach. Discover how enzymes are programmed into microorganisms to catalyze a series of reactions, producing desired compounds. Gain insights into the advantages of PMMA (polymethyl methacrylate) and the importance of developing sustainable alternatives to petroleum-based plastics. Follow along as the video breaks down the steps involved in creating nature-made plastics, from selecting enzymes to optimizing and testing them. Understand the potential impact of this technology on reducing dependence on fossil fuels and creating more environmentally friendly materials.

Synthetic Biology and Materials Science - Nature-Made Plastics

Professor Dave Explains
Add to list
0:00 / 0:00