Explore the critical issue of fatty liver disease in this 21-minute lecture by Dr. Simon W. Beaven from UCLA's Digestive Disease Division. Delve into the complexities of liver function, understanding how it acts as a metabolic "Costco" for the body. Examine the relationship between fat accumulation, insulin resistance, and liver health. Discover various treatment options, including bariatric surgery and vitamin E supplementation. Learn about ongoing research projects and clinical trials, such as the COMET study, aimed at reversing liver disease. Gain insights into the causes of liver disease, with a focus on non-alcoholic steatohepatitis (NASH). Understand the potential for reversing liver damage and the current landscape of chronic liver disease management.