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1
Introduction
2
Upper Tract Urothelial Carcinoma
3
Rare disease
4
Signs and symptoms
5
Grade
6
Treatment
7
Benefits
8
Disadvantages
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Alternative treatments
10
Disadvantages of surgery
11
Medical therapy
12
Upper tract
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New therapy
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Ice gel
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Preclinical work
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In humans
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Trial
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Treatment Paradigms
19
Chemotherapy and Surgery
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Can chemotherapy and surgery improve survival
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The Poud Trial
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Poud Trial Summary
23
Why not chemotherapy after surgery
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Loss of a kidney
25
Who should get chemotherapy before surgery
26
Studies of chemotherapy before surgery
27
Audience Questions
Description:
Explore emerging therapies for upper tract urothelial carcinoma in this informative lecture by UCLA urologist Nicholas Donin, MD. Learn about a novel treatment involving a thermosensitive polymer that enables sustained chemotherapy delivery directly to upper urinary tract tumors. Discover the latest data from a randomized clinical trial, understand the challenges of treating this rare disease, and gain insights into various treatment paradigms. Delve into topics such as disease characteristics, current treatment options, the benefits and drawbacks of surgery, and the potential of combining chemotherapy with surgery to improve patient outcomes. The lecture concludes with a Q&A session addressing audience inquiries.

Emerging Therapies for Upper Tract Urothelial Carcinoma - Nicholas Donin, MD - UCLAMDChat

University of California, Los Angeles
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