Explore the fundamental concepts of population genetics in this comprehensive lecture on drift, inbreeding, and effective population size. Begin with an introduction to probability theory, including random variables, variance, and distributions. Delve into genetic drift through examples and discussions of gamete pools and allele frequencies. Examine how population samples and generational changes affect genetic probabilities over time. Conclude by investigating the roles of mutation and effective population size in shaping genetic diversity. Gain a solid foundation in theoretical frameworks essential for understanding evolutionary processes across biological disciplines.