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How do cells of Saccharomyces cerevisiae behave in a medium containing repressing and including carbon sources
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Erwin Schrodinger 1944
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How do cells of budding yeast behave in a medium containing repressing and inducing carbon sources?
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Diauxie in Bacteria
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Revisiting Diauxie in yeast
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Galactose Catabolism
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Evolution of GAL Genetic Switch in Yeast
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S.cerevisiae GAL switch
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Paradox 1: Long term adaptation
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Paradox 2: Unusual Epistatic interactions in the GAL switch
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"How wounderful that we have met with a paradox, Now we have some hope of making progress"
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Biochemistry or Biochemist? is at odds with Genetics!
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Biochemical data is clearly incompatible with the genetic data
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Gal3p physically interacts with Gal80s-1p
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GAL genetic switch of k.lactis Vs S.cerevisiae
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Would GAL80s-1 GAL4c strain show long term adaptation?
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Ultra-sensitivity of the GAL switch
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Glucose repression is reduced in the mutant strain
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Polygenic evolution of a sugar specialization trade-off in yeast
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Polymorhisms in the yeast galactose sensor underlie a natural contium of nutrient-decision phenotypes
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Diauxie variation is due to polymorphism at GAL3 locus
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Growth on Glucose 0.25% + Galactose 0.25%
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Growth on Melibiose-A disaccharide of Glu and Gal
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Competition between the mutant and wild type
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Gene duplication and the adaptive evolution of a classic genetic switch
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A living vector field reveals constraints on galactose network induction in yeast
Description:
Explore the complex behavior of Saccharomyces cerevisiae cells in media containing repressing and inducing carbon sources in this 92-minute conference talk from the International Centre for Theoretical Sciences. Delve into topics such as diauxie in bacteria and yeast, galactose catabolism, and the evolution of the GAL genetic switch. Examine paradoxes in long-term adaptation and unusual epistatic interactions, and investigate the discrepancies between biochemical and genetic data. Learn about polymorphisms in yeast galactose sensors, growth patterns on various sugar combinations, and gene duplication in the adaptive evolution of genetic switches. Gain insights into the constraints on galactose network induction and the complexities of nutrient decision-making in yeast.

How Do Cells of Saccharomyces Cerevisiae Behave in a Medium Containing Repressing and Including Carbon Sources

International Centre for Theoretical Sciences
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How do cells of Saccharomyces cerevisiae behave in a medium containing repressing and including carbon sources