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1
Intro
2
Objectives
3
Sarcoma Overview
4
Li-Fraumeni Syndrome Testing Criteria
5
Sarcoma in LFS
6
Li-Fraumeni Syndrome • Medical Management can include
7
Surveillance: Toronto Protocol for LFS
8
Survival of TP53 mutation carriers in surveillance and nonsurveillance groups
9
Counseling and Testing issues in LFS
10
Family with Li Fraumeni-like syndrome
11
Familial Adenomatous Polyposis Classic FAP
12
FAP Management
13
Desmoid in FAP
14
Retinoblastoma Monitoring: Secondary
15
Leiomyosarcoma in Hereditary Rb
16
Gastrointestinal Stromal Tumor (GIST)
17
Neurofibromatosis Type
18
Familial GIST: Germline KIT mutation
19
Hereditary GIST Management
20
SDH-deficient GIST: Germline SDHA
21
Rare Inherited Sarcoma Predisposition
22
Summary Clinical Approach
23
Resources
Description:
Explore the world of hereditary sarcoma and genetic counseling in this informative webinar presented by Genetic Counselor Irene Rainville from Ambry Genetics. Gain a comprehensive understanding of major sarcoma subtypes, key syndromes associated with hereditary sarcoma risk, and approaches to genetic diagnosis and management practices. Delve into topics such as Li-Fraumeni Syndrome, Familial Adenomatous Polyposis, Retinoblastoma, Gastrointestinal Stromal Tumor (GIST), and rare inherited sarcoma predispositions. Learn about testing criteria, medical management strategies, and surveillance protocols like the Toronto Protocol for Li-Fraumeni Syndrome. Discover counseling and testing issues, family case studies, and valuable resources for further information. Benefit from Dr. Rainville's expertise in cancer genetics and prevention, particularly in counseling adults with sarcoma and pheochromocytoma paraganglioma syndrome.

Introduction to Hereditary Sarcoma and Genetic Counselling for Sarcoma - Ambry Genetics

Ambry Genetics
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