Explore the cutting-edge field of clinical exome sequencing in this informative lecture from the 2nd Annual Symposium on Clinical Applications of Genome-Wide Testing at UCLA. Delve into the intricacies of exome sequencing, its challenges, and its profound impact on genetic diagnostics. Learn about genetic phenotypes, requisition processes, and examine real-world case studies, including juvenile ALS and Triple A Syndrome. Discover how this revolutionary technology is changing lives and advancing medical research, offering insights into complex genetic disorders and paving the way for personalized medicine.