Delve into an in-depth archival interview with renowned American neuroscientist Paul Greengard, conducted by the Society for Neuroscience on July 23-24, 2001. Explore Greengard's groundbreaking work on the molecular and cellular function of neurons, spanning from his early hypotheses and the skepticism he faced to his revolutionary discoveries in neurotransmitter-regulated protein phosphorylation. Learn about the significance of DARPP-32 in mediating neurotransmitter actions and gain insights into complex molecular signaling in synaptic transmission regulation. Discover the connections between protein phosphorylation and Alzheimer's disease as Greengard shares his life's work and contributions to the field of neuroscience. This 58-minute video, produced by the Educational Film Center, is part of the Society for Neuroscience's "The History of Neuroscience in Autobiography" series, offering a unique glimpse into the life and discoveries of one of neuroscience's most eminent senior researchers. Read more