Главная
Study mode:
on
1
Intro
2
Stochastic Process Algebra
3
Integrated analysis
4
Benefits of integration
5
Outline
6
Modelling in a Data Rich World
7
Molecular processes as concurrent computations
8
Formal modelling in systems biology
9
Bio-PEPA modelling
10
The semantics
11
Optimizing models
12
Alternative perspective
13
Machine Learning Bayesian statistics
14
Comparing the techniques
15
Developing a probabilistic programming approach
16
Probabilistic programming workflow
17
A Probabilistic Programming Process Algebra: ProPPA
18
Example Revisited
19
Constraint Markov Chains
20
Probabilistic CMCS
21
Semantics of ProPPA
22
Simulating Probabilistic Constraint Markoy Chains
23
Calculating the transient probabilities
24
Basic Inference
25
Inference for infinite state spaces
26
Expanding the likelihood
27
Example model
28
Results: ABC
29
Genetic Toggle Switch
30
Toggle switch model: species
31
Experiment
32
Genes (unobserved)
33
Proteins
34
Summary
35
Challenges and Future Directions
Description:
Explore a comprehensive lecture on integrating inference with stochastic process algebra models, delivered by Jane Hillston from Edinburgh at the Alan Turing Institute. Delve into the ProPPA probabilistic programming language, an extension of Bio-PEPA, designed for continuous-time dynamical systems with unknown parameters. Learn about the framework's ability to automate parameter inference algorithms, including a novel MCMC scheme for systems with infinite state-spaces. Discover the application of these techniques in diverse fields such as biology, ecology, and urban transport. Examine the combination of logic and learning in formal methods, and understand the benefits of integrating stochastic process algebra with machine learning and Bayesian statistics. Follow the lecture's progression through topics like molecular processes as concurrent computations, Bio-PEPA modeling, probabilistic programming workflow, and constraint Markov chains. Gain insights into simulating probabilistic constraint Markov chains, calculating transient probabilities, and performing inference for infinite state spaces. Conclude with an exploration of challenges and future directions in this field of study. Read more

Integrating Inference with Stochastic Process Algebra Models - Jane Hillston, Edinburgh

Alan Turing Institute
Add to list
0:00 / 0:00