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1
Intro
2
The Modern Evolutionary Synthesis
3
Theories reconciled through work of Fisher, Haldane, Wright...
4
What's new?
5
Family trees
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A simple model of inheritance
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The simplest imaginable model of inheritance
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Buri's experiment
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Natural populations: Universality
10
What about spatial structure?
11
The Wright-Malécot model
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The pain in the torus (Felsenstein, 1975)
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An individual based model
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Backwards in time
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Patterns of allele frequencies
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The microbe scale
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Visible scales: Emerging (random) structure
18
Hybrid zones and the Allen-Cahn equation
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Zooming out
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Noisy hybrid zones
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The Cahn-Hilliard equation
Description:
Explore the intricate world of genetic variation in this Oxford Mathematics Public Lecture delivered by Alison Etheridge. Delve into the complex interplay of natural selection, mutation, mating, and other genetic, ecological, and evolutionary mechanisms that shape the patterns of genetic diversity observed today. Discover how modern researchers leverage DNA sequencing data and mathematical models to unravel the mysteries of genetic composition in populations. Learn about the evolution of the field from indirect observations of traits to direct analysis of DNA sequences, and understand the crucial role of mathematical caricatures in interpreting genetic data. Journey through topics such as the Modern Evolutionary Synthesis, family trees, inheritance models, spatial structure in populations, and the application of equations like Wright-Malécot, Allen-Cahn, and Cahn-Hilliard in studying genetic patterns across various scales.

Modelling Genes

University of Oxford
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