Explore the dynamics of genomic sequence evolution in adapting budding yeast populations through this insightful lecture by Michael Desai, presented at the Santa Fe Institute's Annual Science Board Symposium and Meeting on New Perspectives in Evolution. Delve into the fascinating world of evolutionary biology as Desai discusses the results of a comprehensive study involving 40 yeast populations, offering valuable insights into the mechanisms of adaptation and genetic change over time. Gain a deeper understanding of how genomic sequences evolve and the implications for broader evolutionary processes in this 55-minute presentation that combines cutting-edge research with accessible explanations.