Explore a comprehensive working group discussion on cognitive regime shifts and brain function breakdown in this 37-minute video from the Santa Fe Institute. Delve into topics such as correlation vs. causation, indicators of functional loss, and multi-level explanations from genetic to behavioral. Examine mechanisms of functional decline, from cellular to network drop-out, and investigate the synthesis of neurology with complexity science concepts. Learn about adaptation and robustness in system aging, network-based risk indicators, criticality in regime shifts, long-range order measurement, and collective dynamics analysis in aging and diseased brains. Gain insights into why systems break, emergence, mind-brain distinctions, healthy vs. broken systems, neural networks, dynamical systems, and recurrent neural networks. Discover how this interdisciplinary approach combines neuroscience with complexity theory to advance our understanding of cognitive decline and brain function.