Explore the complex dynamics of infectious diseases across borders in this 47-minute conference talk from the Santa Fe Institute's Annual Science Board Symposium. Delve into how diseases spread globally, the interplay between human behavior and epidemics, and crucial questions facing healthcare institutions. Examine case studies including the Dutch experience with hospital clusters, SARS reporting strategies, malaria in South Africa, and river blindness. Analyze the strategic substitutes in disease control and the challenges of prompt reporting. Gain insights into the importance of incentives for disease reporting and the global efforts to combat measles. Enhance your understanding of transboundary health issues and their impact on international public health policies.