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1
Intro
2
Disclosures
3
Standard Dose CCTA - Accuracy
4
Core 64
5
Accuracy - CT vs Other Non-Invasive Tests for CAD DX
6
Improving on the Baseline
7
Reduced Dose - Prospective ECG Triggering
8
Radiation Protection - Low kV
9
Simple Measures Go a Long Way
10
Iterative Image Reconstruction
11
Reduced Calcium Blooming Artifacts
12
Improved Specificity for Stenosis
13
Gentle Techniques - TAVR Workup with 40cc Contrast
14
Prognostic Value
15
Prognosis: MUSC Outcomes in 458 Patients
16
Anatomical vs. Functional Testing: PROMISE
17
CT of Cardiac Function (not that)
18
Perfusion CT: An Old Idea...
19
CT Modalities for MPI
20
CT Myocardial Perfusion Protocols: DECT
21
Dual-Source CT Based DECT
22
DECT for Myocardial Ischemia
23
Morphology and Function: DECT
24
DECT Post-processing
25
3rd Gen. DSCT-Based DECT: Radiation-Dose
26
DECT Can Detect Subtle Pathology
27
Delayed Enhancement DECT
28
Extracellular Volume Fraction (ECVF), Novel CT marker for fibrosis
29
Adenosine vs Regadenoson
30
Automated Evaluation Software
31
Quantitative DECT Perfusion
32
Dynamic Time Resolved Perfusion
33
Structure / Function: Comprehensive Dx
34
Absolute MBF Quantification
35
Solving Clinical Dilemmas...
36
Monitoring Therapeutic Effects...
37
3-Vessel Disease: Balanced Ischemia
38
CT Perfusion vs SPECT - Cost Effectiveness
39
CT-FFR: Current Approaches - CFD
40
CT-FFR: The PLATFORM Trial
41
Cost-Effectiveness & Quality of Life
42
CT-FFR: AI - Deep Machine Learning
43
Summary
44
Thank you!
Description:
Explore functional CT imaging techniques for coronary heart disease in this comprehensive lecture by Dr. U. Joseph Schoepf, Associate Professor at the Medical University of South Carolina. Delve into the accuracy of standard dose CCTA and learn about advancements in reduced dose imaging, including prospective ECG triggering and low kV techniques. Discover the benefits of iterative image reconstruction and how it improves specificity for stenosis detection. Examine the prognostic value of CT imaging and compare anatomical vs. functional testing approaches. Investigate various CT modalities for myocardial perfusion imaging, including dual-energy CT (DECT) and its applications in detecting subtle pathologies and quantifying myocardial blood flow. Gain insights into novel CT markers like extracellular volume fraction for fibrosis assessment. Understand the clinical implications of CT perfusion imaging, its cost-effectiveness compared to SPECT, and the emerging role of CT-FFR in diagnosing coronary artery disease. Conclude with an overview of AI and deep machine learning applications in CT-FFR analysis, providing a comprehensive understanding of the latest developments in functional CT imaging for coronary heart disease. Read more

Functional CT Imaging of Coronary Heart Disease

Yale University
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