Explore the ethical implications of human intervention in evolution through this thought-provoking conference talk. Delve into the complex debate surrounding intentional species extinction, examining cases like deadly diseases and the New World screwworm. Investigate the moral dilemma of interfering with nature's processes as new technologies emerge, challenging traditional views on conservation. Analyze the roles of humans as either gardeners or park rangers in shaping ecosystems. Examine CRISPR, gene drive, and sterile insect technology as potential tools for genetic modification. Consider the responsibilities and consequences of altering natural selection, particularly in the context of disease-carrying mosquitoes and malaria prevention. Reflect on the future of immunology, consumer choice, and the balance between genetic manipulation and environmental opportunity in shaping the course of evolution.