Explore the global cyberinfrastructure supporting multi-messenger astrophysics experiments in this 41-minute lecture from the IPAM Workshop on Big Data in Multi-Messenger Astrophysics. Discover how LIGO, Virgo, Kagra, and IceCube utilize a shared infrastructure and learn about its potential to incorporate other astrophysics experiments. Delve into topics such as federation, global compute clusters, content delivery networks, and modular software stacks. Understand the flexibility of the system, including options for single PIs and integration with existing clusters. Gain insights into the longterm vision for regional cell clusters and the open nature of this global cyberinfrastructure, designed to support the entire multi-messenger astrophysics community.