Dive into a comprehensive medical lecture on ulcerative colitis, exploring its symptoms, pathology, and diagnosis. Learn about risk factors, disease classification, and pathophysiology before delving into clinical signs and symptoms, complete with a helpful mnemonic. Understand the disease course, including backwash ileitis, and explore diagnostic methods such as colonoscopy, biopsy findings, and X-ray imaging. Discover the significance of fecal calprotectin levels and gain insights into toxic megacolon. This in-depth video lecture, designed for USMLE and NEET PG preparation, provides a thorough overview of ulcerative colitis, equipping medical students and professionals with essential knowledge for understanding and managing this inflammatory bowel disease.