Explore new approaches and opportunities in auditory research through this comprehensive Grand Round lecture from Stanford Otolaryngology — Head & Neck Surgery. Delve into topics such as the COM Conservation Hearing Study, Stanford Hearing Study, analgesic use, and lifestyle factors affecting hearing health. Gain insights into the big picture of auditory research and discover innovative approaches including multiomics, microbiome studies, and standardization efforts. Learn about the importance of collaboration in advancing the field. Engage with thought-provoking questions on the relationship between hearing and cognition, and understand the delicate balance in auditory health. This informative presentation offers a deep dive into cutting-edge auditory research, providing valuable knowledge for professionals and students in the field of otolaryngology and related disciplines.