Explore the complexities of menopausal hormone therapy in this comprehensive lecture by Dr. Marcia Stefanick, Professor of Medicine at Stanford University. Delve into the controversies surrounding estrogen therapy for perimenopausal women, examining the physiological changes during menopause, common symptoms, and various treatment approaches. Learn about estrogen production, menopause symptoms, lifestyle interventions, and the latest research findings from studies like the Women's Health Initiative and the KEEPS trial. Gain insights into the effects of hormone therapy on osteoporosis, dementia, and overall aging. This informative talk provides valuable knowledge for women navigating the menopausal transition and healthcare professionals seeking to understand the latest developments in hormone therapy.