Explore the intricacies of celiac disease in this comprehensive lecture by Dr. Nielsen Fernandez-Becker from Stanford University. Delve into the history, prevalence, and pathophysiology of this genetically linked autoimmune disorder triggered by gluten consumption. Learn about the various clinical manifestations, diagnostic methods including genetic testing, blood tests, and endoscopic findings, and understand the differences between celiac disease, non-celiac gluten sensitivity, and wheat allergy. Gain insights into the challenges of monitoring treatment adherence and managing non-responsive cases. This informative talk covers everything from the basic physiology of the small intestine to the complexities of celiac disease management, providing valuable knowledge for healthcare professionals and individuals interested in this increasingly recognized condition.