Explore a keynote presentation on high-throughput diagnostics and sequencing at the Pandemic Response Lab in New York City. Delve into the efforts to control the spread of SARS-CoV-2 through widespread testing and monitoring of emerging variants. Learn about the CoV2 test principle, virus inactivation, RNA extraction, and sample processing pipeline. Discover the equipment stoichiometry, sample tracking, and analysis using the DaViD system. Examine current optimization work, including pooled testing and at-home saliva collection. Investigate the integrated CoV2 whole genome sequencing pipeline, development timeline, and variant growth over time. Analyze NYC variant distributions, focusing on B.1.1.7 and B.1.526 +E484K strains. Gain insights into the executive team, Scientific Advisory Board, and the dedicated professionals behind these crucial pandemic response efforts.