Explore the global preclinical antibacterial pipeline in this 38-minute conversation with Valeria Gigante, Team Lead at the World Health Organization's AMR Division. Delve into the process of reviewing the antibacterial pipeline, recognize progress and gaps in antibiotic discovery, and identify opportunities to overcome hurdles in early-stage antibacterial research and development. Gain insights on bacterial priority pathogen lists, research targeting, innovation challenges, pipeline composition, and future prospects. Understand the importance of antibiotic discovery in combating antimicrobial resistance and the economic challenges faced by the field. Learn about the latest WHO report on preclinical and clinical antibacterial development, methodologies used, and the composition of current pipelines, including IND-enabling phases and mechanism of action considerations.