Explore the pharmacology of Warfarin in this comprehensive lecture, covering its mechanism of action, indications, adverse drug reactions, and contraindications. Delve into the role of Vitamin K in the coagulation cascade, understand how Warfarin functions as an anticoagulant, and learn about its effects on various proteins involved in blood clotting. Examine important drug interactions, prophylactic uses, and applications in conditions such as atrial fibrillation. Gain insights into monitoring Warfarin therapy through PT/INR tests, and become aware of potential adverse reactions, including bleeding risks, liver failure concerns, and pregnancy-related issues. Enhance your knowledge of this crucial anticoagulant medication to better understand its clinical applications and potential risks.