Explore the complexities of utilizing virtual populations in oncology drug development in this 18-minute lecture by Trachette Jackson from the University of Michigan. Delve into the challenges faced when implementing mathematical models to simulate patient responses and optimize cancer treatments. Gain insights into the intersection of mathematical oncology and drug development, focusing on resistance mechanisms and treatment optimization strategies. Part of the Fields Institute's Thematic Program on Mathematical Oncology, this talk contributes to the broader discussion on mathematical modelling of cancer treatments and resistance.