Explore a comprehensive conversation with FDA Commissioner Robert Califf on protecting public health, covering topics from baby formula shortages to vaccine authorizations. Delve into the FDA's regulatory responsibilities, including its oversight of $2.7 trillion worth of food, medical products, and tobacco. Examine controversial decisions such as the COVID-19 vaccine authorization, menthol cigarette ban, and infant formula plant shutdown. Investigate the agency's limitations in dietary supplement regulation, drug pricing influence, and food import inspections due to resource constraints. Gain insights into pressing health issues like the Roe v. Wade decision, e-cigarette regulations, the opioid crisis, and combating health disinformation. Learn about the FDA's efforts to rebuild public trust and navigate conflicts of obligation in its mission to protect public health.