Explore the indications, techniques, and complications of bone marrow transplantation in sickle cell disease in this 45-minute lecture. Delve into the pathophysiology, donor selection process, and various stem cell sources. Learn about conditioning agents, pre-transplant discussions, and the ideal regimen for BMT in SCD. Examine common complications such as graft-versus-host disease, posterior reversible encephalopathy syndrome, sinusoidal obstruction syndrome, and transplant-associated microangiopathy. Gain insights into the challenges faced during BMT for sickle cell patients and understand the current treatment approaches.