Learn about hemolytic anemia in this comprehensive lecture on hematology. Explore the classification, causes, and mechanisms of this condition characterized by the destruction of red blood cells. Discover the differences between inherited and acquired forms of hemolytic anemia, and delve into extra-erythrocytic disorders and red blood cell abnormalities that can lead to this condition. Gain insights into various factors such as immune abnormalities, mechanical trauma, drug-induced hemolysis, and infections that contribute to hemolytic anemia. Examine intrinsic defects of red blood cells, including membrane abnormalities, enzyme deficiencies, and hemoglobin disorders. Understand the complexities of thalassemia and abnormal hemoglobin structures, as well as the role of erythrocyte membrane proteins in the development of hemolytic anemia.