Explore key aspects of antibiotic management in this comprehensive lecture, covering treatment duration, pre-procedure prophylaxis, and antibiotic lock therapy. Learn about the evolution of standard care regarding antibiotic duration and typical recommendations for common bacterial infections in adults. Discover when and how to narrow antibiotic coverage, including empiric stepwise narrowing. Gain insights into antibiotic prophylaxis strategies and understand the principles of antibiotic lock therapy. Enhance your knowledge of these critical topics in antimicrobial stewardship to improve patient care and combat antibiotic resistance.