Explore the complex interplay between human behavior, social factors, and infectious disease spread in this 45-minute colloquium talk by Shigui Ruan from the University of Miami. Delve into topics such as social behavior, research fraud, anti-vaccine movements, game theory, and social inequality. Examine case studies including Rift Valley Fever and the Feast of Sacrifice, while considering the impact of socio-economic activities and psychological factors on disease transmission. Gain insights from simulations and a comprehensive analysis of circular psychological factors to better understand the multifaceted nature of public health challenges in the context of infectious diseases.