Explore the clinical and genetic determinants of contralateral breast cancer in this informative webinar presented by Dr. Katharine Yao, Chief of Surgical Oncology at NorthShore University HealthSystem. Delve into the risk factors for contralateral breast cancer in newly diagnosed patients, with a particular emphasis on the impact of family history and genetic mutations. Learn about the application of risk models and prediction tools in clinical settings. Gain insights into treatment preferences, bilateral mastectomy rates, and the effects of anti-estrogen treatment and radiation therapy on contralateral breast cancer risk. Examine the prevalence of genetic mutations across different racial and ethnic groups, and understand the implications of BRCA and non-BRCA genes on contralateral breast cancer risk. Discover the Manchester Guidelines, prediction models, and their clinical applications. Analyze the relationship between contralateral prophylactic mastectomy and survival rates, considering potential selection biases. Conclude by exploring patient motivations for choosing contralateral prophylactic mastectomy. Read more