Explore the complexities of prednisone use in rheumatology and autoimmune disease treatment in this informative 21-minute video. Learn about the revolutionary glucocorticoid's mechanisms, applications, and tapering strategies. Discover the HPA axis, various synthetic cortisol forms, and appropriate dosing. Understand why rheumatologists prescribe prednisone and how to conceptualize its use through the "rope and bridge" analogy. Gain insights on when to use prednisone, its benefits in treating inflammatory conditions, and effective methods for discontinuing its use.