Explore cutting-edge techniques and ideas in radiation oncology through this comprehensive physician grand rounds presentation. Delve into effective radiation planning, considerations, and requirements for ablative therapy. Understand the rules of thumb for conventional fractionation and learn why altering fractionation schemes can be beneficial. Examine key terms and factors affecting effective dose, including Biologically Effective Dose. Investigate the role of radiotherapy in metastatic disease, focusing on the clinical approach to oligometastatic disease and its efficacy. Discover the history and potential of the Abscopal Effect, from its origins in 1953 to recent developments in 2014. Gain valuable insights into the latest advancements and future possibilities in radiation oncology treatment.