Learn about immunotherapy and checkpoint inhibitor drugs in this comprehensive physician grand rounds presentation. Explore the biology of immune checkpoints, PD1 inhibitors for melanoma treatment, and combination therapies using CTLA4 and PD1 blockade. Examine adjuvant checkpoint inhibitor treatments for melanoma, including ipilimumab and PD1 inhibitors. Discover the use of checkpoint inhibitors in advanced non-small cell lung cancer (NSCLC) and as adjuvant therapy after chemoradiotherapy for stage III NSCLC. Gain insights into predictors of response and strategies for managing toxicity associated with these treatments. This 52-minute lecture, delivered by Dr. Joseph Merchant from McFarland Clinic's Hematology/Oncology department, provides a comprehensive overview of targeted immunotherapy approaches in cancer treatment.