Learn about blood transfusion practices, blood products, and patient blood management in this comprehensive physician grand rounds presentation. Explore the history of transfusions, various blood components, and their clinical applications. Gain insights into proper indications for red cell transfusions, plasma administration, and platelet transfusions. Discover strategies for massive transfusions, managing transfusion reactions, and preventing circulatory overload. Examine evidence-based approaches to blood management and understand key takeaway points for improving patient care while optimizing blood utilization in clinical practice.