Explore a comprehensive analysis of USB security vulnerabilities and defenses in this 18-minute conference talk presented at the 2018 IEEE Symposium on Security & Privacy. Delve into the evolution of USB-based attacks, examining their increasing complexity and diverse attack vectors. Gain insights into the fragmented defensive measures developed by the security community in response to these threats. Discover a systematic categorization of USB attacks and defenses, identifying offensive and defensive primitives across various communication layers within the USB ecosystem. Learn about the trust-by-default nature of USB and how attacks often transcend different software stack layers. Examine the first formal verification of the USB Type-C Authentication specification, uncovering fundamental flaws in its design. Conclude with an exploration of future research directions aimed at enhancing USB security and ensuring safer computing experiences.