Explore the significance of Human Leukocytic Antigen-B27 (HLA-B27) in this informative 12-minute video from Medicosis Perfectionalis. Delve into the association between HLA-B27 and various rheumatological conditions, including psoriatic arthritis, ankylosing spondylitis, inflammatory bowel disease-associated arthritis, reactive arthritis, and acute anterior uveitis. Learn about the role of HLA-B27 as part of the major histocompatibility complex (MHC) class I. Gain insights into the prevalence of HLA-B27 in healthy Caucasians and its implications for rheumatological diseases and postinfectious syndromes. Enhance your understanding of this important genetic marker and its relevance in medical diagnostics and patient care.