Explore the crucial roles of Protein C and Protein S in blood coagulation through this informative 12-minute video lecture. Delve into the function of these vitamin K-dependent factors as inhibitors of active factors Va and VIIIa in secondary hemostasis. Learn about their production in the liver, the importance of gamma carboxylation, and their relationship with thrombomodulin. Discover the genetic disorder Factor V Leiden and its impact on hypercoagulability. Gain insights into protein C deficiency, thrombosis, and warfarin-induced skin necrosis. Reinforce your understanding with a quiz at the end of the lecture, making this an essential resource for medical and nursing students studying hematology and coagulation disorders.