Explore novel search methods for detecting primitive and intelligent life beyond Earth in this comprehensive lecture by Harvard astronomer Abraham (Avi) Loeb. Delve into cutting-edge techniques for identifying potential life forms in our solar system and around nearby stars, examining the possibility of early life after the Big Bang and its long-term cosmic prospects. Learn about astronomers' vocabulary, biology far from Earth, detection techniques for artificially-illuminated objects, and methods for identifying bio-markers in planetary atmospheres. Discover upcoming technological advancements like the James Webb Space Telescope and Extremely Large Telescopes, and investigate intriguing concepts such as industrial pollution detection, panspermia, and the transfer of life between galaxies. Gain insights into the habitable epoch of the universe and the potential for life in unexpected places, from Mars and Europa to white dwarf systems.