Explore the complex relationship between cannabis use and impaired driving in this lecture from the 2nd Annual UCLA Interdisciplinary Cannabis Symposium. Delve into research findings presented by Dr. Thomas Marcotte, Professor of Psychiatry and Co-director of the Center for Medicinal Cannabis Research at UCSD. Examine the challenges of measuring cannabis impairment, including the poor correlation between blood THC levels and actual impairment. Learn about ongoing studies using driving simulators and on-road assessments to evaluate the effects of cannabis on driving performance. Discuss the impact of cannabis legalization on road safety and the development of performance-based approaches for detecting impairment. Gain insights into the complexities of establishing legal limits for cannabis-impaired driving and the potential use of oral fluid testing for roadside assessments.