Explore KubeEdge-powered edge devices with next-generation cloud-native runtime in this conference talk. Dive into the challenges of cloud-native edge computing, including the need for lightweight container sandbox technology and unified cross-architecture runtime solutions. Learn about KubeEdge and iSula, and discover how WebAssembly and WASI are revolutionizing edge computing. Compare Docker and WebAssembly, examine various WebAssembly runtimes, and understand the architecture and scheduler design of WasmEngine. Gain insights into future developments in this rapidly evolving field of edge-cloud synergy and multi-architecture system migration.